Hyperglycemia Associated with Olanzapine Treatment

Abstract

Olanzapine is an atypical antipsychotic clinically very effective in the treatment of schizophrenia and related psychoses with better efficacy and tolerability than older generation antipsychotics. Recently there are flurry of reports that olanzapine is associated with high blood sugar levels in new onset of diabetes mellitus or pre-existing diabetes mellitus. The authors report a series of diabetes associated with olanzapine treatment from Indian context. The clinical implications this emerging side effect is discussed.