Parathyroid Carcinoma, Parathyroid Crisis and Hungry Bone Syndrome Publishing Date: 21 December 2020

Abstract

Parathyroid carcinoma is a rare endocrine malignancy accounting for <1% of cases of sporadic primary hyperparathyroidism (PHPT) and is associated with more severe clinical disease than its much more common benign counterpart, parathyroid adenoma.  Clinical suspicion of a parathyroid cancer, therefore, should lead the surgeon to an aggressive initial operative approach as a complete resection of all malignant tissue at the time of initial surgery allows for the greatest likelihood of a cure. We report a case of parathyroid carcinoma induced parathyroid crisis with development of hungry bone syndrome in the postoperative period.