A Rare Case of Anti-Phospholipid Antibody Syndrome with Bleeding Manifestation

Abstract

The Antiphospholipid syndrome or Antiphospholipid antibody syndrome (APS or APLS), is an acquired autoimmune thrombophilic disorder in which patient have vascular thrombosis and/or pregnancy complications attributable to placental insufficiency accompanied by presence of anti-phospholipid antibodies in blood. Bleeding manifestations are uncommon in APS. Prolongation of aPTT is an usual manifestation of APS but not accounting for any bleeding manifestations. In rare occasions, a hemorrhagic diathesis can occur due to the occurrence of anti-prothrombin antibodies causing severe hypoprothrombinemia.

We are reporting a case Antiphospholipid Syndrome with rare atypical bleeding manifestations.