Serotonin-Norepinephrine Reuptake Inhibitors

Abstract

Serotonin-Norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant used in the treatment of major depression and other mood disorders. SNRIs were developed more recently than SSRIs, and there are relatively few of them. Their efficacy as well as their tolerability appears to be somewhat better than the SSRIs'. Abrupt discontinuation of SNRI- medication usually leads to a discontinuation syndrome which could include states of anxiety and further symptoms. The most common side effects include nausea, drowsiness, headache, changes in appetite, vivid dreams etc.